Kayla Houghton1

F, #118711

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
Birth2

Citations

  1. [S1536] Interview, unknown informant, from Ashly Houghton Fink, July 2021.
  2. [S1536] Interview, unknown informant, from Ashley Houghton Fink, July 2021.

Garrett Houghton1

M, #118712

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
Birth2

Citations

  1. [S1536] Interview, unknown informant, from Ashly Houghton Fink, July 2021.
  2. [S1536] Interview, unknown informant, from Ashley Houghton Fink, July 2021.

Jeremy Loebach1

M, #118713

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
Birth3

Citations

  1. [S1536] Interview, unknown informant, from Ashly Houghton Fink, July 2021.
  2. [S415] E-mail from Christine S. Logsdon, June 8, 2022.
  3. [S1536] Interview, unknown informant, from Ashley Houghton Fink, July 2021.

Bridgette Loebach1

F, #118714

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
Birth2

Citations

  1. [S1536] Interview, unknown informant, from Ashly Houghton Fink, July 2021.
  2. [S1536] Interview, unknown informant, from Ashley Houghton Fink, July 2021.

Blake Loebach1

M, #118715

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
Birth2

Citations

  1. [S1536] Interview, unknown informant, from Ashly Houghton Fink, July 2021.
  2. [S1536] Interview, unknown informant, from Ashley Houghton Fink, July 2021.

Jacob Loebach1

M, #118716

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
Birth3

Citations

  1. [S1536] Interview, unknown informant, from Ashly Houghton Fink, July 2021.
  2. [S415] E-mail from Christine S. Logsdon, June 8, 2022.
  3. [S1536] Interview, unknown informant, from Ashley Houghton Fink, July 2021.

Joey King1

M, #118717

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
Birth2

Citations

  1. [S1536] Interview, unknown informant, from Ashly Houghton Fink, July 2021.
  2. [S1536] Interview, unknown informant, from Ashley Houghton Fink, July 2021.

Stephen Houghton1

M, #118718, b. circa 1988

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
Birthcirca 1988WA, USA1

Citations

  1. [S1536] Interview, unknown informant, from Ashley Houghton Fink, July 2021.

Daryl David Houghton Jr1

M, #118719, b. circa 1996

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
Birthcirca 1996WA, USA1

Citations

  1. [S1536] Interview, unknown informant, from Ashley Houghton Fink, July 2021.

Maria Houghton1

F, #118720, b. circa 1999

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
Birthcirca 1999WA, USA1

Citations

  1. [S1536] Interview, unknown informant, from Ashley Houghton Fink, July 2021.

Michael Vern Houghton1

M, #118721, b. circa 1988

Family: Samantha (?)

Biography

Corresponded with authorN
A Contributor to Houghton Surname ProjectN
Birthcirca 1988MI, USA2
Marriage3

Citations

  1. [S1536] Interview, unknown informant, from Ashly Houghton Fink, July 2021.
  2. [S1536] Interview, unknown informant, from Ashley Houghton Fink, July 2021.
  3. [S415] E-mail from Ashly Houghton Fink, June 8, 2022.

April Rose Houghton1

F, #118722, b. circa 1986

Family: Kris Masters

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
Birthcirca 1986MI, USA3
Children+Together they had 3 children and have adopted 6 children. They now (2022) have a total of 9.
Trevin Masters (age 16)
Teegen Masters (age 13)
Karsin Masters (age 9)
Gavin Masters (age 9)
Parker Masters (age 9)
Danika Masters (age 7)
Zaity Masters (aqe 6)
Za'Rae Masters (age 6)
Kristopher Masters Jr. (age 1)4
Marriage4

Citations

  1. [S1536] Interview, unknown informant, from Ashly Houghton Fink, July 2021.
  2. [S1536] Interview, unknown informant, from Ashly
    Houghton Fink, July 2021.
  3. [S1536] Interview, unknown informant, from Ashley Houghton Fink, July 2021.
  4. [S415] E-mail from Ashly Houghton Fink, June 8, 2022.

Andrew Jacob Houghton1

M, #118723, b. circa 1992

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
Birthcirca 1992MI, USA2

Citations

  1. [S1536] Interview, unknown informant, from Ashly Houghton Fink, July 2021.
  2. [S1536] Interview, unknown informant, from Ashley Houghton Fink, July 2021.
  3. [S415] E-mail from Ashly Houghton Fink, June 8, 2022.

Dr. Kyle Fink PhD1

M, #118724, d. January 1984

Family: Ashly Sharae Houghton b. c 1987

Biography

Corresponded with authorN
A Contributor to Houghton Surname ProjectN
DeathJan, 1984
Education2008University of California, Davis, Medical Center, Stem Cell Program
Sacramento, California
Ruth L. Kirchstein NRSA Postdoctoral Scholar, Institute for Regenerative Cures, Stem Cell Program, 2016

University of Nantes
Nantes, France
Ph.D., Neuroscience, INSERM UMR643, 2013

Central Michigan University
Mount Pleasant, Michigan
Ph.D., Neuroscience, Field Neurosciences Institute of Restorative Neurology, 2013

Central Michigan University
Mount Pleasant, Michigan
M.S., Experimental Psychology, 2010

University of Portland
Portland, Oregon
B.A., Psychology with Neuroscience Focus, The BRAIN Lab, 2008
Marriage2
OccupationUC Davis, Davis, CA, USA, Assistant Professor
Neurology and Institute for Regenerative Cures
Living2022West Sacramento, CA, USA
Note2022UC Davis, Website: Research Interests

Dr. Fink received his Ph.D. in Neuroscience from Central Michigan University and the University of Nantes. He has focused on therapeutic development for neurodegenerative diseases, brain injury, and some forms of brain cancer. His research team focuses on genetically-linked neurological disorders such as CDKL5 deficiency (rare intractable pediatric epilepsy), Angelman’s Syndrome, and Huntington’s disease that are targetable with gene editing molecules in addition to some forms of brain cancer. His lab is identifying candidate sequences through whole genome sequencing and transcriptomics using a bioinformatics approach for structural variation discovery and genotyping that identify underlying common genetic variants. Gene variants linked to disease phenotype are examined for “actionable domains” for which we create therapeutic artificial transcription factors. Patient-derived samples can be used to create in vitro neuronal disease-in-a-dish models using novel induced neuron techniques. His team builds on the existing strengths and expertise at UC Davis and utilizes the necessary resources to develop a therapeutic pipeline in which precision medicine can be used to identify novel disease causing genetic variants to advance Precision Neurotherapeutics to clinical applications.

His current research focuses on two major goals 1) The therapeutic application of transcription activator-like effector (TALE) and clustered regularly interspaced short palindrome repeats (CRISPR) to modify gene expression in genetically-linked pediatric neurological diseases; and 2) the development of delivery systems that can safely and efficaciously target the central nervous system with our novel gene editing platforms. These goals specifically address: A) how to deliver these potent therapeutics to maximize the biodistribution in the central nervous system; B) how to increase the specificity of each construct to limiting off-target effects; and C) how to minimize the immune response to increase safety and the therapeutic potential of this approach. They have used known information regarding JHD and CDKL5 deficiency to guide construction of potent, precise gene modifying modalities- CRISPR/Cas9 and TALE. These platforms can turn on or enhance transcription of a gene, transcriptionally silence expression, cause permanent epigenetic changes, or remove a piece of DNA via targeted double stranded breaks essentially allowing for custom modifications to be made at the genomic level.

Citations

  1. [S1536] Interview, unknown informant, from Ashly Houghton Fink, July 2021.
  2. [S1536] Interview, unknown informant, from Ashley Houghton Fink, July 2021.
  3. [S415] E-mail from Ashly Houghton Fink, June 8, 2022.

Sharon Ranay1

F, #118725, b. circa 1964

Family: William Vern Houghton b. 26 Jul 1959, d. 26 Sep 2003

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
Birthcirca 1964
Marriage

Citations

  1. [S415] E-mail from Ashly Houghton Fink, June 8, 2022.

Adriana C. Strunk

F, #118726, b. 13 December 1951

Family: Stanley Ray Houghton b. 25 Jan 1952

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
BirthDec 13, 1951
Marriage

Carmen Anita Houghton

F, #118727, b. 19 February 1974

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
BirthFeb 19, 1974

Bridgette C. Houghton

F, #118728, b. 22 February 1976

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
BirthFeb 22, 1976

Cheryl Lynn Houghton

F, #118729, b. 17 November 1971

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
BirthNov 17, 1971

Darrill Lee Houghton

M, #118730, b. 1 February 1946, d. 9 October 1955

Biography

Corresponded with authorN
A Contributor to Houghton Surname ProjectN
BirthFeb 1, 1946
DeathOct 9, 1955

Michelle Elaine Houghton

F, #118731, b. 1970

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
Birth1970

Beatrice Velma Houghton

F, #118732, b. 1921, d. 1962

Biography

Corresponded with authorN
A Contributor to Houghton Surname ProjectN
Birth1921
Death1962

George Jewison Houghton

M, #118733, b. 1922, d. 1922

Biography

Corresponded with authorN
A Contributor to Houghton Surname ProjectN
Birth1922
Death1922

Steven Roy Houghton

M, #118734, b. 1924, d. 1924

Biography

Corresponded with authorN
A Contributor to Houghton Surname ProjectN
Birth1924
Death1924

Earl C. Morgan1

M, #118735, b. 1 June 1893, d. 15 December 1935

Family: Mildred E. Houghton b. 31 Jul 1893, d. 21 Oct 1978

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
BirthJun 1, 18931
MarriageJun 19, 1918NY, USA, New York State, Marriage Index, 1881-19671
DeathDec 15, 1935Buffalo, NY, USA1

Citations

  1. [S415] E-mail from Christine S. Logsdon, 21 Feb 2022.

Ruth Weyant1

F, #118736, b. 8 July 1892, d. October 1979

Family: Earle Henry Houghton b. 17 Nov 1888, d. 27 Oct 1954

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
BirthJul 8, 1892Weedsport, Cayuga Co., NY, USA1
Marriage1
No Childrn
1950 US Census1950Syracuse, NY, USA, age 61, no occup
DeathOct, 1979CA, USA1

Citations

  1. [S415] E-mail from Christine S. Logsdon, 21 Feb 2022.

Lawrence Harold Spencer1

M, #118737, b. 24 July 1897, d. 31 December 1959

Family: Anna L. Houghton b. 8 Mar 1899, d. 13 Jul 1955

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
BirthJul 24, 1897Akron, OH, USA1
MarriageJun 14, 1919Houghton, NY, USA1
Children+1920Elaine Louise Spencer
Birth: 25 March 1920, Houghton, New York Reference: U.S., Social Security Application and Claims Index, 1936-2007
Death: 16 Dec. 2001, DeLeon Springs, Florida Reference: U.S., Social Security Application and Claims Index, 1936-2007

Don Houghton Spencer
Birth: 2 Nov 1921, Akron, Summit, Ohio Reference: Ohio, U.S. Birth Index, 1908-1998
Death: 24 Sep 1943. Lost at sea during WWII, US NAVY, Submarine USS Grayling off Manila, Philippines declared lost with all hands, KIA/MIA

Ruth Vivian Spencer
Birth: 30 June 1925, Summit, Ohio Reference: Ohio, U.S. Birth Index, 1908-1998
Death: 13 Apr 1933, Warsaw, Wyoming, New York Reference: New York State, Death Index, 1852-1956

Muriel Frances Spencer
Birth: 30 Oct 1932, Warsaw, New York. Reference: New York State Birth Index, 1881-1942
Death: Living1
DeathDec 31, 1959Attica, NY, USA1

Citations

  1. [S415] E-mail from Christine S. Logsdon, 21 Feb 2022.

Harold W. Harter1

M, #118738, b. circa 1904

Family: Velma G. Houghton b. 25 May 1906, d. Dec 1992

Biography

Corresponded with authorN
A Contributor to Houghton Surname ProjectN
Birthcirca 19041
MarriageMay 30, 19261

Citations

  1. [S415] E-mail from Christine S. Logsdon, 21 Feb 2022.

Margareth Sinclair

F, #118739

Family: James Lester Houghton b. 23 Sep 1915, d. 18 Oct 2002

Biography

Corresponded with authorN
A Contributor to Houghton Surname ProjectN
MarriageJun 17, 2000Lebanon, Or, USA

(?) DeWolfe

M, #118740

Family: Anita Marlene Houghton b. c 1939, d. 2015

Biography

A Contributor to Houghton Surname ProjectN
Corresponded with authorN
Marriage